DRUG BLOG

DRUG BLOG

DOMPERIDONE

Who should NOT take this medication?

Do not take domperidone if you:

• are allergic to domperidone or any ingredients of the medication
• are taking the medication ketoconazole
• are taking medications which cause QT prolongation
• have bleeding in the stomach or intestines
• have a blockage in the stomach or intestines
• have breaks in the lining of the stomach or intestines
• have a prolactinoma (a tumour of the pituitary gland)
• have uncorrected levels of potassium, magnesium, or calcium in your blood
• have cardiac disease (e.g., heart failure)
• have QT prolongation (a type of irregular heartbeat)
• have moderate or severe liver impairment

METRONIDAZOLE

TRIVIA: The antibacterial activity of metronidazole was discovered by accident in 1962 when metronidazole cured a patient of both trichomonad vaginitis and bacterial gingivitis 

PANTOPRAZOLE

The best time to take Pantoprazole

- It's usual to take pantoprazole once a day, first thing in the morning. If you take pantoprazole twice a day, take 1 dose in the morning and 1 dose in the evening. It's best to take pantoprazole an hour before a meal. Swallow tablets whole with a drink of water.

TRAMADOL

Tramadol: Don't Make It A Habit

Even though tramadol is not a full opiate -- it's thought it also exhibits weak inhibition of reuptake of norepinephrine and serotonin -- people with a history of drug abuse may be at a greater risk of addiction. Tramadol is related to the opioids like codeine and morphine and can lead to psychological and physical dependence, drug-seeking behavior, and withdrawal. Short-term use of tramadol is the best option.

If you are concerned you are becoming addicted, talk to your doctor about alternative pain medicines. As previously mentioned, tramadol should not be stopped abruptly. Withdrawal symptoms may occur if you are dependent upon tramadol, but may be lessened by a slow, dose reduction combined with symptomatic support, as directed by your doctor.

METOCLOPRAMIDE

How long can you take metoclopramide?

Metoclopramide oral is taken for only 4 to 12 weeks. NEVER USE METOCLOPRAMIDE IN LARGER AMOUNTS THAN RECOMMENDED, OR FOR LONGER THAN 12 WEEKS. High doses or long-term use of metoclopramide can cause a serious movement disorder that may not be reversible.

KETOROLAC

Important Information

You should not use ketorolac if you have any active or recent bleeding (including bleeding inside your body), a head injury, a stomach ulcer, severe kidney disease, a bleeding or blood-clotting disorder, a history of severe allergic reaction to aspirin or an NSAID, if you are scheduled to have surgery, if you are in late pregnancy, or if you are breast-feeding a baby.

You should not use ketorolac if you also take pentoxifylline, probenecid, aspirin, or other NSAIDs.

Ketorolac can increase your risk of fatal heart attack or stroke, especially if you use it long term or take high doses, or if you have heart disease. Do not use ketorolac just before or after heart bypass surgery (coronary artery bypass graft, or CABG).

Ketorolac may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using ketorolac, especially in older adults. You should not take this medicine if you already have bleeding in your stomach or intestines.

AMINOLEBAN

OVERVIEW 

AMINOLEBAN is a formulated nutritional formula for patients with chronic liver impairment. It is a nutritional supplement that contains high concentration of Branched-chain amino acids.

PARACETAMOL

TRIVIA: Paracetamol was first used by German physician, Joseph von Mering, on his patients in 1887, after it was created by Harmon Northrop Morse, an American chemist, ten years earlier.

REBAMIPIDE

ALL ABOUT REBAMIPIDE

Rebamipide is administered for the treatment of gastritis, peptic ulcer and other gastric disorders. It belongs to a class of antacids or anti-reflux agents. It is known to be effective in the treatment for gastro duodenal ulcers. It helps to enhance the mucosal defence system. It is also known to decrease free radicals of oxygen in the body and also increasing intestinal blood flow.

REFERENCES:

https://chealth.canoe.com/drug/getdrug/dom-domperidone

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC89320/

https://www.nhs.uk/medicines/pantoprazole/

https://www.drugs.com/slideshow/tramadol-facts-1192

https://www.rxlist.com/reglan-drug/patient-images-side-effects.html

https://www.drugs.com/mtm/ketorolac-oral-injection.html

https://otsuka.pk/product.php?id=28

http://tenrandomfacts.com/paracetamol/

https://www.lybrate.com/medicine/rebamipide